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Additionally, no significant differences were observed in the incidence rate per 1000 person-years of diabetes (18.4 vs 22.7), dyslipidemia (43.5 vs 39.4), and cardiovascular disease (22.9 vs 16.2) between those with NAFLD and NASH (figure)

proposed that weight gain may represent an independent clinical feature of hyperprolactinemia, and reported a markedly increased prevalence of obesity in affected patients ( Consistent with these observations, several case series and retrospective reports have identified unexplained early weight gain, and in some cases, presentation of symptoms in patients later diagnosed with prolactinomas ( In a large retrospective analysis of 219 patients newly diagnosed with pathological hyperprolactinemia, Colao et al

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After 5 days without adverse effects, researchers typically increase to 0.5mg daily, then 0.75mg if needed, with 1.0mg daily as the absolute ceiling