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Collectively, these findings highlight the potential for early identification and intervention to prevent the progression of diabetic cardiomyopathy in patients with concurrent CKD

References Lopresti AL, Smith SJ, Metse AP, Drummond PD

doi: 10.1371/journal.ppat.1005972 170 TripathiDRadhakrishnanRKThandiRSPaidipallyPDevalrajuKPNeelaVSKet al

Firstly, PLSCR1 can bind to EGFR and enhance its phosphorylation level, which may interfere with the efficacy of many drugs targeting EGFR (eg: Lapatinib)