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But fibroblasts can't conjure collagen from nothing - they need amino acid building blocks, particularly glycine, proline and hydroxyproline

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dNTP pools in replicating cells are at a low steady-state concentration and are rapidly turned-over, indicating that the precursors are polymerized into DNA almost immediately upon their production (Rottgen and Rabes, 1989)

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Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism