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Therefore, ME2 has two functions in mitochondria: the first is producing pyruvate and NADH to generate ATP through oxidative phosphorylation, and the second is generating NADPH to counteract ROS

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After quality control, pre- and post-treatment measurements of IC/VC VOIs were available for 52/53 and 46/53 patients, respectively, whereas data at both time points were available for 43/50 patients

Aiming to lower the risk factors of diabetes such as atherosclerosis, myocardial infarction, and coronary diseases (Petrie, Guzik, & Touyz, 2018), combined quercetin and metformin therapy was found to improve the lipid profile, decrease triglycerides and total cholesterol, and reduce serum levels of low-density lipoprotein and high-density lipoprotein

Caveolin-1 Caveolae and caveolar proteins are implicated in the regulation of multiple functions within cells (23, 93, 103)