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Cagrilintide trials have shown weight loss results of roughly 2023% in certain combination study arms, making it one of the most closely studied amylin receptor agonists in current clinical investigation

Published mouse studies did not report overt toxicity, liver-enzyme issues, or sickness-related weight loss at 25-50 mg/kg IP for up to 8 weeks

Serial measurements taken under consistent conditions (same time of day, same fasting state) are more informative than single measurements

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