A significant increase in its value was observed 24 hours after the intervention, and a significant decrease 48 hours after the intervention, as compared to its value after 24 hours (Paired T-test, 1 tailed, p=0.002, p=0.0005 respectively) ( Figure 1 )
Hospitalized patients with severe COVID-19 show high levels of IL-2, IL-7, IL-10, G-CSF, TNF, CXCL10, MCP1, and MIP1 in serum [6], suggesting that severe COVID-19 is dictated as a cytokine release syndrome (CRS), which is a disorder induced by cytokine storms [12,13,14]
Based on the pooled data across all evaluated PD-1/PD-L1 inhibitors, the eight most frequently reported respiratory adverse eventsdyspnoea, pneumonia, pneumonitis, interstitial lung disease, cough, pleural effusion, respiratory failure, and immune-mediated lung diseasewere selected to establish a common baseline for subsequent analyses
SLIM1 is a member of the EIL family transcription factors, ETHYLENE-INSENSITIVE3-LIKE3 (EIL3), and controls the sulfate starvation response of a large number of, but not all, responsive genes (Maruyama-Nakashita et al., 2006
Scavenger receptors are critical in mediating efferocytosis, including SR-A, SR-F, and SR-H families (262, 264, 322325)
