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10.1038/s41598-021-85972-2 19 IhlenfeldtW

Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation

Toxics [Internet]

Nicotinamide analogs such as 6-methylaminonicotinamide form one class of NNMT inhibitors that work by mimicking the natural substrate, NAM, and competing for the enzymes active site 197