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Although 8-oxodG predominantly induces G:CT:A transversion [152154], bypass of this lesion in mammalian cells can also lead to G:CA:T transition and G:CC:G transversion [124, 155]

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By July 2024 manufacturers will have to ensure the warnings are on all king-size cigarettes sold, and by April 2025 all regular-size cigarettes and little cigars with tipping paper and tubes must include the warnings

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Some people find the first cigarette rewarding if they are under stress, for example, which Grieders previous research suggests is thanks to nicotines ability to reduce the negative effects of stress