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In an initial longitudinal study of severely ill CAD patients who had collectively sustained 49 cardiac events in the 8 years before enrollment, adherent patients achieved a mean total cholesterol reduction from approximately 246 mg/dL to 137 mg/dL, and none experienced a recurrent cardiac event over the 12-year follow-up

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characterizing over the counter vitamin A supplements found that at least three were teratogenic and four contained doses that exceed the recommended daily level of intake

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