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Oxidative stress or other stress stimuli induce the dissociation of the Nrf2-Keap1 complex, resulting in Nrf2 nuclear translocation and subsequent binding to the antioxidant response element (ARE) in the regulatory region of the target genes

Oft gibt es dafr Grnde: ein stressiger Arbeitstag, intensive sportliche Anstrengungen, schlechter Schlaf oder gar die Folgen einer Erkrankung wie Post/Long Covid, Fibromyalgien oder sogar Burnout

Four-in-one antibodies have superior cancer inhibitory activity against EGFR, HER2, HER3, and VEGF through disruption of HER/MET crosstalk

We need human-proximal systems (patient-derived organoids, microphysiological chips, single-cell redox omics) validated against clinical panels (species footprint iron) and functional outcomes

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