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Akiyama H, Zhao R, Ostermann LB, Li Z, Tcheng M, Yazdani SJ, et al

Using 3T3 fibroblasts as a skin model, secretomes were separated through Fast Protein Liquid Chromatography (FPLC) after inducing cellular distress

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As the avidin-biotin affinity interaction is so strong, therefore it is usually impractical to elute biotinylated targets that have been captured to immobilize avidin or streptavidin support

study (1998) compared four topical treatments on human skin over one month, with immunohistological analysis of skin biopsies (actual tissue samples examined under a microscope)