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She says: The more prevalent, disruptive effects of alcohol use on sleep include more frequent awakenings, worse sleep quality resulting from a reduction of deep sleep and increase of restless REM sleep stage, alongside earlier than usual waking times, leading people to feel that they didn't get enough sleep. If you have a condition like sleep apnoea, drinking alcohol can make it much worse

pneumoniae was studied using techniques such as tandem mass tag (TMT) labeling, which is a chemical labeling technique used in mass spectrometry to identify relative protein abundance, and liquid chromatography mass spectrometry (LC-MS) metabolomics, which helps to separate, identify, and quantify metabolites