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Cancer Metastasis Rev 38(12):205222 Rajeshkumar NV, Yabuuchi S, Pai SG et al (2017) Treatment of pancreatic cancer patient-derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin

doi: 10.1016/j.rsma.2020.101242 509 SagawaN.KawaaiK.HinataH

Mol Neurobiol 54(7):55735582 Zhu X, Dubey D, Bermudez C, Porter BE (2015a) Suppressing cAMP response element-binding protein transcription shortens the duration of status epilepticus and decreases the number of spontaneous seizures in the pilocarpine model of epilepsy

GSTP1 detoxifies arsenic-based drugs by isolating the active site and dimer interface, reacting with cysteine in the presence of sufficient GSH under low GSH conditions (48,49)

Open communication with your healthcare team ensures optimal management of both your diabetes and vitamin B12 status, supporting long-term health and wellbeing whilst continuing the benefits of metformin therapy