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Elevated Hcy levels in mice result in diminished levels of mature insulin receptors across various tissues, culminating in IR and the onset of T2D (Zhang et al., 2021)

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Por el contrario, en los hmsters, el aumento de los carcinomas nasales y larngeos fue insignificante

This interaction occurs due to the ability of PFs to suppress CRH gene expression in the hypothalamus and to modulate the neuroendocrine stress pathways responsible for the downstream effects of CORT