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These enzymes achieve this by catalyzing the nucleophilic attack of the thiol group of glutathione on electrophilic centers of various substrates

Biomedicines 9 , 1296 (2021)

Nutrients 15(7):1732 Kim M et al (2023) 2-Deoxy-d-ribose induces ferroptosis in renal tubular epithelial cells via ubiquitin-proteasome system-mediated xCT protein degradation

10.1186/s12916-015-0537-7 [DOI] [PMC free article] [PubMed] [Google Scholar] ciskalska M., Zalewska M., Grzelak A., Milnerowicz H

Additionally, green tea catechins have been suggested to decrease intestinal medication absorption by blocking OATP uptake, increasing P-gp export activity, or reducing drug solubility (198)