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Vitamin D deficiency is observed in SLE patients and also reported to be linked with disease activity

This significantly strong interaction force implies that the incorporation of Fe 2+ facilitates the assembly of HCFe nanozymes, thereby enhancing the stability of the nanostructures

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In a more specific embodiment, L is a lysosomal protease-sensitive linker, and W comprises a cleavable peptide moiety, for example selected from the group consisting of valinecitrulline (Val-Cit), alanine-alanine-asparagine (Ala-Ala-Asn), valine-alanine (Val-Ala) and phenylalanine-lysine (Phe-Lys)