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Your body makes glutathione from three amino acids: cysteine, glycine and glutamate

J Anim Physiol Anim Nutr 102:3340 Suh SH, Lee KE, Kim IJ, Kim O, Kim CS, Choi JS, Choi HI, Bae EH, Ma SK, Lee JU, Kim SW (2015) Alpha-lipoic acid attenuates lipopolysaccharide-induced kidney injury

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Alternative approaches include supplementing with precursor nutrients such as N-acetylcysteine (NAC), which the body can use to synthesise glutathione naturally, though NAC is also not recommended for NAFLD in NICE guidance and should not be self-prescribed for liver disease

Although they are effective in reducing disease incidence, the high heterogeneity among individuals in terms of genetics, lifestyle choices, and environmental factors necessitates the search for establishment of targeted treatment strategies