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The target sequence GTGTCAGGAGGTGTTTGGAAAG (SEQ ID NO: 2) was inserted into pSUPER vector (Oligoengine, Seattle WA) which drives endogenous production of shRNA under the HI promoter

PC-C: Data curation, Writing review & editing

Timing is important in reproductive care

The commenters noted that more precise definitions will ensure that hospitals are interpreting the specifications correctly and patients will have more accurate data to allow them to make more informed decisions