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Doubtful Justification of the Gluten-Free Diet in the Course of Hashimotos Disease

3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)

NAD + deficiency accelerates aging Multiply evidence elucidates that NAD + and NAD + -related metabolites govern biological functions in aging, including metabolism, redox homeostasis, mitochondria function and the circadian clock

Another study showed that low levels of vitamin B12 may be linked with poor cognitive performance

Malnutrition : Especially in the elderly, cancer patients, or children whose growth is slowing down