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Diet, gut microbiome, and bone health

Indeed, oxidative stress hampers chromatin reprogramming including DNA methylation, which has important consequences on the formation of the protamine shield protecting DNA from oxidative stress and thereby DNA damage

The activation of protease-activated receptor 2 (PAR2) triggers an inflammatory response by phosphorylating Nuclear factor kappa-light-chain enhancer of activated B cells (NF-B) and Forkhead box O 6 (FoxO6) through the Protein kinase B (Akt) pathway, which could serve as a crucial mechanism for ROS-induced inflammation (51)

Licochalcone A is a Liquorice derivative that has anti-inflammatory and soothing effects

doi: 10.1172/jci29444