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BER enzymes are primarily targeted at removing N7-MeG and N3-MeA lesions, subsequently repairing the DNA through the collaborative action of DNA polymerase and DNA ligase, thus restoring the DNA strand to its original, non-damaged state [165]

*Correspondence: Mohd Esa Norhaizan [email protected] Present Address: Heshu Sulaiman Rahman, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor, Malaysia

Infections may also occur

It consists of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) and is widely studied in preclinical models for tissue repair, angiogenesis, gastroprotection, and tendon/ligament healing

Positive results are usually reported four to six weeks after the last session and continue to improve for several weeks following the treatment