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For these initial efficacy studies, we elected to test drugs with one dose of ionizing radiation rather than conducting fractionated radiation doses to minimize tissue damage and animal stress

7 : 123130 Zhou Y, Kok KH, Chun AC, Wong CM, Wu HW, Lin MC, Fung PC, Kung H and Jin DY (2000) Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis