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Neuropsychiatr Dis Treat 7:3949 Andersen J, Taboureau O, Hansen KB, Olsen L, Egebjerg J, Stromgaard K, Kristensen AS (2009) Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants

Optional: If the lysate is too viscous, add RNase A (10 g/mL) and DNase I (5 g/mL) and incubate on ice for 10-15 minutes

Immune System Support By protecting cells from oxidative stress, glutathione helps support overall defense mechanisms

Zincarelli C, Soltys S, Rengo G, Rabinowitz JE

For example, enhancing oxidative phosphorylation in microglia might promote a more quiescent, neuroprotective state, while targeted inhibition of glycolysis could reduce harmful inflammation (Barros et al., 2009