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Since metabolic activity directly controls cellular proliferation, it may be more difficult for the tumor cells to overcome a metabolic inhibition to develop resistance, Huang said

Vitamin C (200 mg) is a potent antioxidant that shields cells from free radicals, protecting DNA, cell membranes, and other structures

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Second, cancer cells are highly adaptable and can activate compensatory antioxidant pathways, like the thioredoxin system, to survive GSH inhibition, reducing therapeutic effectiveness