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Treatment sessions can be repeated several times a week or several times a month, depending on the patient's condition

Down-regulation of SelF in cancer cell lines leads to up-regulation of p21 and p27 (cell cycle inhibitors) and subsequently induces a slowdown in cellular proliferation and triggers a state of growth arrest specifically in colon and liver cancer cells (205207)

If the damage is irreparable, p53 initiates apoptosis to eliminate abnormal cells (Liu et al., 2024

The beneficial effects of NO donors in patients with intrauterine growth retardation (IUGR) and inhibition of pre-term labor has been studied [149, 150]