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Ethics declarations Ethics approval and consent to participate This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics

N -carbamoyl-l-glutamic acid N -Carbamoyl-l-glutamic acid (NCG or Carbaglu) is a structural analogue of N -acetyl glutamate (NAG) that restores urea cycle function in inherited NAGS and CPS1 deficiency [45]

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