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The intrathecal administration of the 5-HT 3 receptor antagonist (ondansetron) reversed mechanical and cold hypersensitivity of paclitaxel-treated rats

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These outcomes together confirmed that these plant metabolites are promising substances to reduce the health consequences of AFs

Further exploration of the ways in which cellular glutamine status affects these diverse processes, as well as the investigation of strategies that cells may adopt to withstand glutamine limitation, may uncover new intersections between metabolism and disease, revealing novel opportunities for therapeutic intervention