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29-mer/alginate gel treatment caused extensive expansion of CD146 + TSPC in their niche on postoperative day 2, followed by infiltration of CD146 + /BrdU TSPC into the injured tendon on day 7

TB-500 has a broader systemic healing effect

Methionine is then converted into S-adenosylmethionine (SAM), which donates methyl groups in reactions catalyzed by methyltransferases, including DNA methylation, producing S-adenosylhomocysteine (SAH) that is converted back into homocysteine

Collectively, these advances underscore how PBN is propelling MI/R treatment into an era of precision damage control and repair