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Luciferase reporter assay A luciferase reporter plasmid, a TK-Renilla (thymidine kinase promoter-Renilla) plasmid, and other indicated plasmids were transfected into HEK293T cells using polyethylenimine

Interestingly, the outcomes showed that the application of PPs (e.g., curcumin and resveratrol) to alleviate health-related complications of AFs has increased during the last 10 years due to the health-promoting effects of these natural metabolites

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Several studies have suggested that UPS is involved in the regulation of anti-oxidants, such as catalase, heme oxygenase-1 (HO-1), copper/zinc-superoxide dismutase and -GCS [1821]

This is dependent on angiotensin II type-1 and mineralocorticoid receptors [136]