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Six RCTs had a duration treatment of 12 weeks [13, 1618, 32, 33], and two RCTs had a duration treatment of 24 weeks [34, 35]

For example, phosphatidylcholine, choline, and -carnitine from egg, dairy products, and red meat can be metabolized by specific gut bacteria to produce trimethylamine (TMA), which is subsequently oxidized to trimethylamine-N-oxide (TMAO) by hepatic flavin monooxygenase 10,11,12