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Aggregates of alpha-synuclein (syn) phosphorylated at serine 129 (PSER129) are hallmarks of synucleinopathies, which, for PD/DLB, are found predominantly in neurons, whereas in MSA, aggregates are primarily found in oligodendroglia

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Moreover, some tumor cells that resist radiotherapy and chemotherapy can change to the secondary form of glioblastoma lesions and cause tumor recurrence