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In addition, hypoxia also promotes the formation of tumor neovascularization, enhances the invasion of tumor cells, and damages the function of T cells in many ways, such as glucose deprivation, extracellular adenosine accumulation and enhanced expression of immune checkpoints (130, 132)

& Hanafusa, T

Integrative Medicine (Encinitas) , 2014 (reduced vs oxidized glutathione and antioxidant role)

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[PUBMED Abstract] Leahy AB, Newman H, Li Y, et al.: CD19-targeted chimeric antigen receptor T-cell therapy for CNS relapsed or refractory acute lymphocytic leukaemia: a post-hoc analysis of pooled data from five clinical trials