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The presented results and earlier findings indicate that a high expression of ASPN in ovarian stromal cells could be an indicative marker gene of tumor progression in ovarian stroma

Escalation: Move to 4 mg weekly for Weeks 58, then 8 mg weekly for Weeks 912 [1]

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When administered in this way, serious (although rare) adverse effects can occur, including vision loss, stroke, paralysis, and death

It is the reason the FDA's career scientists spent months reviewing the evidence and arrived at a unanimous negative recommendation before a panel whose composition may not be positioned to weigh that evidence independently