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In fact, oxidative stress is increasingly recognised as a contributing factor in stone formation, and glutathione's antioxidant function may have a modest protective effect on renal epithelial cells that are vulnerable to crystal adhesion

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Gut Pathog 15 , 30 (2023)

For instance, in breast cancer, E-cadherin has an unexpected regulatory ability in tumorigenicity and hypoxia responses: E-cadherin loss is associated with slower tumor growth and loss of hypoxia response genes, which lead to reduced glycolytic capacity