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Therefore, authors suggested that LC supplementation may be effective in obese and overweight subjects

Preservation of Lean Muscle Mass: Unlike some weight-loss approaches, L-Carnitine may help preserve lean muscle tissue while promoting fat loss

The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-alpha 2b plus ribavirin

This counteracting effect of L-carnitine was dose-dependent and statistically significant at least at 4 h of exposure (Figure 6)

In their meta-analysis combining the results of twelve randomized controlled trials, Veronese and colleagues reported a significant decrease in depression severity after acetylcarnitine supplementation as monotherapy compared with placebo intake or no intervention [143]