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Description

C-terminal modification of macrocycles For fluorescein- or biotin-labelling of aMD5, aMD5-Lys(Mmt)-NH-resin was synthesized by Fmoc SPPS and the Mmt group was then deprotected using 98% dichloromethane, 1% TFA and 1% triisopropylsilane

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However, in vitro inhibition of compound 13 ( SPB07393SC ) was found to be the most effective against Glo-I enzyme Fig

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The British Journal of Dermatology

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