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9 reported for the first time in 1990 that the doseresponse curve obtained by acetylcholine in patients with hypertension was smaller than the curve in normal controls and that the doseresponse curves obtained by sodium nitropreside were similar in the two groups, suggesting that endothelial function, but not smooth muscle function, is selectively impaired in patients with hypertension, a large number of studies have shown that hypertension is associated with endothelial dysfunction

Trace expression of the germ-cell alkaline phosphatase gene in human placenta

Ageing and epigenetics Epigenetic regulation is used to classify heritable changes in gene expression that are not attributable to changes in DNA sequences

The interplay between eating time, peripheral circadian rhythms and hormonal fluctuations may represent a fundamental mechanism linking eating habits to metabolic diseases