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Elevated NNMT activity has been associated with increased fat accumulation, reduced metabolic efficiency, and impaired cellular energy production

Its a process called somatic hypermutation

Similar to diluted almond extract

In some embodiments, the invention encompasses a method of providing muscular therapy by co-administering a therapeutically effective amount of one or more NNMT inhibitors with one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increase intracellular NAD+ levels to provide muscular therapy

The problem that the team were trying to resolve was how to prevent elderly patients, hospitalised with Covid, from worsening to the point of needing respiratory machinery, after which outcomes were poor