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Effect of vitamin b12 levels on the association between folic acid treatment and ckd progression: A post hoc analysis of a folic acid interventional trial

Hormonal interactions are not a documented concern at research doses

As we noted in the CY 2025 OPPS/ASC final rule with comment period (89 FR 94514 through 94521), we believe that a methodological change to increase the importance of the Safety of Care measure group is appropriate