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The utilization of a small molecular chaperone exhibited the ability to restore the native wild-type conformation of NQO1 and a substantial enhancement in the enzymatic activity of the P187S variant protein [264]

However, NTAPP did not induce a statistically significant elongation of hHFs in the ex vivo organ culture model (data not shown), and Ki-67+ keratinocytes in matrix were not significantly increased in NTAPP-exposed hHFs (Supplementary Figure 6)

After he takes a certain amount of damage he turns into his second stage

doi: 10.1186/s12888-023-04666-3 131 YaoY.WalshW