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10.1002/biof.1716 BioFactors

Such glucose and oxygen deprivation can lead to decreased MHC class I antigen presentation in cancer cells, rendering them unresponsive to IFN-mediated cytotoxic effects due to STAT1 dysfunction

These results suggest that Renca VEGFR2-Fc and B16F10 VEGFR2-Fc tumors keep growing in vivo by escaping from abrogation of the VEGF signaling pathway, even though tumor growth was delayed due to inhibition of tumor angiogenesis by VEGFR2-Fc