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Moreover, pyroglutamic acid possesses antimicrobial, antidiabetic and anti-hyperlipidemic properties 31 , suggesting that S

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BSO buthionine sulfoxime Landscapes Health & Medical Sciences (AREA) Life Sciences & Earth Sciences (AREA) Animal Behavior & Ethology (AREA) Public Health (AREA) Chemical & Material Sciences (AREA) Veterinary Medicine (AREA) Medicinal Chemistry (AREA) General Health & Medical Sciences (AREA) Pharmacology & Pharmacy (AREA) Epidemiology (AREA) Bioinformatics & Cheminformatics (AREA) Engineering & Computer Science (AREA) Environmental Sciences (AREA) General Chemical & Material Sciences (AREA) Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA) Chemical Kinetics & Catalysis (AREA) Organic Chemistry (AREA) Molecular Biology (AREA) Zoology (AREA) Biodiversity & Conservation Biology (AREA) Animal Husbandry (AREA) Cell Biology (AREA) Heart & Thoracic Surgery (AREA) Cardiology (AREA) Pulmonology (AREA) Vascular Medicine (AREA) Urology & Nephrology (AREA) Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA) Thiazole And Isothizaole Compounds (AREA) Abstract A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1,2,3,4-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue

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