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The clean reads were mapped to the human genome (GRCh38) using HISAT2

Metabolic vulnerabilities and targeted therapies This reliance on mitochondrial respiration exposes a specific therapeutic vulnerability

For the duration of the study and short while afterwards, It was observed that there appeared to be a gradual rise in the concentration of growth hormones in all subjects

Further prospective clinical trials are needed to determine whether the initial use of metformin can effectively prevent TB infection after exposure or simply mitigate the progression from LTBI to active disease