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Rainer BM, Kang S, Chien AL

We've found that chronic studies often require careful monitoring for any potential compensatory mechanisms

Once cellular DNA is severely damaged by cisplatin, nuclear PARP-1 activity is increased, causing AIF activation and nuclear translocation, which induces apoptosis [37]

We've seen how dramatically the right treatment can change someone's lifefrom the executive who got her energy back to the new mum who finally felt like herself again