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Kim SA, Jang JH, Kim W, Lee PR, Kim YH, Vang H, Lee K, Oh SB (2022) Mitochondrial reactive oxygen species elicit acute and chronic itch via transient receptor potential canonical 3 activation in mice

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As shown in Figure 4, without mitochondria or lysosomes, RBCs possess no self-repair mechanisms and must rely entirely on enzymatic and non-enzymatic antioxidant systems