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TNF- activates multiple signaling pathways through binding to its receptors (TNFR1 and TNFR2), inducing the release of inflammatory mediators, cell proliferation, apoptosis, and immune cell recruitment, ultimately leading to chronic intestinal inflammation

The study provides new insight into the potential benefits of Metformin and could lead to the development of new treatments for pain

Effects of Bugu Shengsui decoction on related indicators of oxidative stress and Ferroptosis in rats with osteoporosis

Vitamin C is a key antioxidant for immune function and tissue repair

Specifically, the function of the gut microbiota impacts host iron absorption, while iron homeostasis in the host also influences the diversity, classification, function, and dominant bacterial community of the microbiota [65]