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Structural snapshots of RAF kinase interactions

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There are hundreds of other non-protein-associated amino acids which combine in unique ways to perform a number of functions beyond protein synthesis, including tissue growth and repair, central nervous system and neurological function, gut integrity, immune health, gene expression regulation, and detoxification

These continuously generated electrophilic hydroperoxy-phospholipids are neutralized by a specific GSH-dependent peroxidase, glutathione peroxidase 4 (GPX4), which prevents them from damaging membranes and driving ferroptotic cell death (7, 8)

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