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Zhang J, Wang H, Yan X, Zhang L

Science 376 , eabh1623 (2022)

FFAs also indirectly cause mitochondrial injury by inducing lysosomal permeabilization, which causes activation of pro-apoptotic members of the Bcl-2 family that subsequently induce mitochondrial permeabilization and apoptotic cell death [70, 71]

Principal component analysis Gene expression data consists of 204 human cell lines (observations) from two different known groups (Resistant group (R) and Sensitive group (S)) described by 193 genes (variables)

However, the scope of both changes, although statistically significant, was within the limits of accepted norms for healthy people