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Parallel to the availability of cranberry polyphenols, resveratrol is found in red wine and it undergoes rapid metabolism in the small intestine and by the gut microbiota, leading to low plasma bioavailability and complex outcomes (Galiniak et al., 2019)

assay for DNA cleavage or mutation at the target sequence, or assay for altered gene expression activity affected by CRISPR complex formation and/or CRISPR enzyme activity), as compared to a control no exposed to the CRISPR enzyme or complex, or exposed to a CRISPR enzyme lacking the one or more NLSs