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It is due to difficulties of interpretation such as these that the underlying factors discussed previously must also be taken into account to keep each set of experiments in the correct context, as differences in behaviour may be due to environmental differences rather than cognitive differences

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Yale J Biol Med

For topical use, transient local reactions redness, stinging, burning, or itch are the expected category and are exactly what the ongoing Phase 2 trial is set up to measure (NCT07437586)